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This homeostatic modulation, rather than directional stimulation, suggests a fundamentally different mechanism than most vasodilators
Cell supernatants and lysates were plated on 7H11 agar medium (Hi Media, Santa Maria, CA, USA) enriched with ADC (GEMINI, USA) and incubated at 37C for three weeks to evaluate mycobacterial growth or survival under treatment conditions by counting the colony-forming units (CFUs)
Symptoms and treatments vary from one patient to another
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and broad transcriptional effects, with gene-expression analyses identifying modulation of expression patterns associated with antioxidant defense, DNA repair, and tissue remodeling
